科研项目： （1） 核酸外切酶III辅助信号放大SERS传感界面构建及其检测DNA甲基转移酶的研究（国家自然科学基金），2018.01－2020.12，主持 （2） 新型磁控SERS纳米探针对DNA甲基转移酶活性及抑制剂筛选的研究（山东省自然科学基金），2017.08-2019.12，主持 （3） 基于双臂型DNA四面体骨架的电子介体-辅酶-脱氢酶仿生传感界面的构建及应用（国家自然科学基金），2019.01-2021.12，参与 （4） 基于功能化碳材料的脑内神经活性物质电化学检测新方法的研究（国家自然科学基金），2018.01-2021.12，参与 （5） 协同稳定双链核酸适体探针的设计与电化学传感应用（山东省自然科学基金），2018.08-2021.12，参与 代表性论文： (1) Jiahui Wen, Yongming Liu, Jingwen Li, Hao Lin, Yiran Zheng, Yan Chen, Xiuli Fu* and Lingxin Chen, * A label-free protamine-assisted colorimetric sensor for highly sensitive detection of S1 nuclease activity, Analyst, 2020, 145, 2774–2778 （通讯作者，影响因子3.978） (2) Xiuli Fu, Jiahui Wen, Jingwen Li, Hao Lin, Yongming Liu,* Xuming Zhuang, Chunyuan Tian, Lingxin Chen, Highly sensitive detection of prostate cancer specific PCA3 mimic DNA using SERS-based competitive lateral flow assay, Nanoscale, 2019, 11, 15530–15536 （影响因子6.895） (3) Xiuli Fu, Yunqing Wang, Yongming Liu, Huitao Liu, Longwen Fu, Jiahui Wen, Jingwen Li, Peihai Wei, Lingxin Chen, A graphene oxide/gold nanoparticle-based amplification method for SERS immunoassay of cardiac troponin I, Analyst, 2019, 144, 1582–1589 （影响因子3.978） (4) Xiuli Fu, Lingxin Chen*, Jaebum Choo*, Optical Nanoprobes for Ultrasensitive Immunoassay, Analytical Chemistry, 2017, 89: 124-137 （影响因子6.785） (5) Xiuli Fu, Ziyi Cheng, Jimin Yu, Lingxin Chen, Jaebum Choo*，A SERS-based Lateral Flow Assay Biosensor for Highly Sensitive Detection of HIV-1 DNA, Biosensors and Bioelectronics, 2016, 78: 530-537（影响因子10.257） (6) Xiuli Fu, Lingxin Chen*, Jinhua Li, Meng Lin, Huiyan You, Wenhai Wang, Label-Free Colorimetric Sensor for Ultrasensitive Detection of Heparin Based on Color Quenching of Gold Nanorods by Graphene Oxide，Biosensors and Bioelectronics, 2012, 34: 227-231 （影响因子10.257） (7) Xiuli Fu, Tingting Lou, Zhaopeng Chen, Meng Lin, Weiwei Feng, Lingxin Chen*, "Turn-on" Fluorescence Detection of Lead Ions Based on Accelerated Leaching of Gold Nanoparticles on the Surface of Graphene, ACS Applied Materials & Interfaces, 2012, 4(2): 1080-1086 （影响因子8.758） (8) Xiuli Fu, Lingxin Chen*, Jinhua Li, Ultrasensitive Colorimetric Detection of Heparin Based on Self-assembly of Gold Nanoparticles on Graphene Oxide, Analyst, 2012, 137: 3653-3658 （影响因子3.978） (9) Lingxin Chen*, Xiuli Fu, Jinhua Li, Ultrasensitive Surface-Enhanced Raman Scattering Detection of Trypsin Based on Anti-Aggregation of 4-Mercaptopyridine-Functionalized Silver Nanoparticles: an Optical Sensing Platform Toward Proteases, Nanoscale, 2013, 5: 5905-5911 （影响因子6.895） (10) Ling Chen, Xiuli Fu, Wenhui Lu, Lingxin Chen*, Highly Sensitive and Selective Colorimetric Sensing of Hg2+ Based on The Morphology Transition of Silver Nanoprisms, ACS Applied Materials & Interfaces, 2013, 5: 284-290 （影响因子8.758） (11) Xiaokun Wang, Ling Chen, Xiuli Fu, Lingxin Chen*, Yangjun Ding, Highly Sensitive Surface-Enhanced Raman Scattering Sensing of Heparin Based on Anti-Aggregation of Functionalized Silver Nanoparticles, ACS Applied Materials & Interfaces, 2013, 5:11059-11065 （影响因子8.758，） (12) Wei Qin*, Rongning Liang, Xiuli Fu, Qianwen Wang, Tanji Yin, Wenjing Song, Trance-Level Potentiometric Detection in The Presence of a High Electrolyte Background, Analytical Chemistry, 2012, 84: 10509-10513（影响因子6.785） 专著： Lingxin Chen*, yunqing wang, Xiuli Fu, Ling chen, Novel optical nanoprobes for chemical and biological analysis, Springer Briefs, 2014 授权发明专利： （1）秦伟*，梁荣宁，付秀丽，宋文璟，王倩文，张倩玉，一种基于非对称性聚合物膜的传感器及其检测方法和应用，2014.03.12，中国，申请号：ZL201010622842.2 （2）秦伟*，付秀丽，一种检测低浓度重金属离子的方法及其装置，2014.07.30，中国，申请号：ZL201010225887.6 获奖情况： 烟台大学第二届“教学质量奖” |
